In Vitro Propagation and Pharmacological Potential of Crateva adansonii DC: Biotechnological Advances and Bioactive Profiles

Author(s): SM Sangle and Vaibhav Kute

Abstract:

Crateva adansonii DC. (Capparaceae) is a medicinal tree of significant ethnomedicinal value in West Africa and South Asia, widely utilised for the treatment of inflammation, renal disorders, and metabolic diseases. Despite its therapeutic importance, the species faces existential threats from habitat fragmentation and unsustainable harvesting, necessitating urgent conservation interventions. This review synthesises current knowledge regarding the botanical characteristics, phytochemical constituents, and pharmacological activities of C. adansonii, with a specific focus on in vitro propagation protocols as a tool for germplasm conservation. Analysis of existing literature reveals that while micropropagation has been achieved using nodal and shoot tip explants, reproducibility remains a challenge due to inconsistent reporting of hormonal requirements and acclimatisation protocols. Phytochemical investigations have identified diverse secondary metabolites, including triterpenes (e.g., lupeol), flavonoids, and glucosinolates; however, significant intraspecific variability in metabolite profiles complicates standardisation. We identify critical research gaps, particularly the lack of voucher specimen citations in experimental studies and the need for optimised elicitation strategies to enhance secondary metabolite production. This review advocates for the integration of biotechnological tools with rigorous phytochemical profiling to ensure the sustainable utilisation and conservation of this threatened medicinal species.

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Pages: 111-118     |    16 View     |    2 Download