Phytochemical Profiling and GC–MS Analysis of Psoralea corylifolia Linn

Author(s): Dr. Tripti Bisaria

Abstract:

Psoralea corylifolia Linn. (Babchi) is an important medicinal plant widely used in traditional systems of medicine for the treatment of skin disorders and other chronic ailments. Its therapeutic efficacy is attributed to the presence of diverse bioactive phytochemicals such as furanocoumarins, flavonoids, and phenolic compounds. Phytochemical profiling using modern analytical techniques is essential to scientifically validate its medicinal value. Gas chromatography–mass spectrometry (GC–MS) is a reliable tool for identifying volatile and semi-volatile constituents in plant extracts. The present study focuses on phytochemical screening and GC–MS analysis of Psoralea corylifolia Linn. To elucidate its chemical composition and potential pharmaceutical significance. Qualitative phytochemical screening revealed the presence of flavonoids, phenolics, terpenoids, coumarins, fatty acids, and glycosides. GC–MS analysis identified eighteen major bioactive compounds, including bakuchiol, psoralen, isopsoralen, phytol, linoleic acid, oleic acid, and hexadecanoic acid. These compounds are reported to possess antioxidant, antimicrobial, anti-inflammatory, and dermatoprotective properties. The results provide scientific validation for the traditional use of P. corylifolia and highlight its potential as a valuable source of bioactive natural products.

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